2×12 refers to a speaker configuration using two 12-inch speakers, commonly found in guitar amplifier cabinets. This setup delivers a bigger, fuller sound than a single speaker, with increased low-end response, projection, and overall volume.

A 2×12 cabinet offers a strong balance between power and portability, providing much of the depth and punch of larger cabinets without the size and weight of a 4×12. It is popular for live performance and studio use, especially with high-powered amp heads and driven tones.